- Patent Title: Pharmaceutical composition for treatment of bone-related disease
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Application No.: US16617757Application Date: 2018-05-30
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Publication No.: US11253498B2Publication Date: 2022-02-22
- Inventor: Jung Taek Seo , Seok Jun Moon , Sung Jin Kim
- Applicant: Nexyon Biotech Co., Ltd.
- Applicant Address: KR Seoul
- Assignee: Nexyon Biotech Co., Ltd.
- Current Assignee: Nexyon Biotech Co., Ltd.
- Current Assignee Address: KR Seoul
- Agency: McDonnell Boehnen Hulbert & Berghoff LLP
- Priority: KR10-2017-0068400 20170601,KR10-2018-0005406 20180116,KR10-2018-0055737 20180516
- International Application: PCT/KR2018/006174 WO 20180530
- International Announcement: WO2018/221966 WO 20181206
- Main IPC: A61K31/37
- IPC: A61K31/37 ; A61P19/10 ; A61K45/06

Abstract:
The present invention relates to a pharmaceutical composition for preventing or treating a bone-related disease; and the pharmaceutical composition is very effective in preventing or treating bone-related diseases in that it not only promotes differentiation of preosteoblast cells into osteoblasts to induce production of mineralized nodules, but also, at the same time, inhibits differentiation of bone marrow cells into osteoclasts and the function of osteoclasts so that bone homeostasis is effectively regulated. In addition, the present invention relates to a pharmaceutical composition for preventing or treating a menopausal disease, in particular, a menopausal bone disease; and the pharmaceutical composition is very effective in preventing or treating a menopausal bone-related disease in that it not only increases the volume of trabecular bone and promotes differentiation of preosteoblast cells into osteoblasts to induce production of mineralized nodules, but also, at the same time, inhibits differentiation of bone marrow cells into osteoclasts and the function of osteoclasts so that bone homeostasis is effectively regulated.
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