Invention Grant
- Patent Title: Method and system for suspension culture
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Application No.: US15328763Application Date: 2015-07-09
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Publication No.: US11254903B2Publication Date: 2022-02-22
- Inventor: Michelle Louise Janas , Aaron Dulgar Tulloch , Clive Glover
- Applicant: Cytiva Sweden AB
- Applicant Address: SE Uppsala
- Assignee: Cytiva Sweden AB
- Current Assignee: Cytiva Sweden AB
- Current Assignee Address: SE Uppsala
- Agency: Eversheds Sutherland (US) LLP
- Priority: GB1416362 20140916
- International Application: PCT/EP2015/065683 WO 20150709
- International Announcement: WO2016/012249 WO 20160128
- Main IPC: C12M1/00
- IPC: C12M1/00 ; C12M3/06 ; C12M1/34 ; C12M1/36 ; C12N5/0783

Abstract:
The present invention relates to cell culture in bioreactors, such as flexible cellbag bioreactors. More closely the invention relates to a method and system for determining the cell density in a bioreactor culture and for controlling the perfusion rate of a suspension culture of cells in a bioreactor, comprising measuring the oxygen uptake of primary mononuclear cells in a non-static bioreactor.
Public/Granted literature
- US20170211027A1 METHOD AND SYSTEM FOR SUSPENSION CULTURE Public/Granted day:2017-07-27
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