Invention Grant
- Patent Title: Processes for production of tumor infiltrating lymphocytes and uses of same in immunotherapy
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Application No.: US17353430Application Date: 2021-06-21
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Publication No.: US11254913B1Publication Date: 2022-02-22
- Inventor: Seth Wardell , James Bender
- Applicant: Iovance Biotherapeutics, Inc.
- Applicant Address: US CA San Carlos
- Assignee: Iovance Biotherapeutics, Inc.
- Current Assignee: Iovance Biotherapeutics, Inc.
- Current Assignee Address: US CA San Carlos
- Agency: Morgan, Lewis & Bockius LLP
- Main IPC: C12N5/0783
- IPC: C12N5/0783 ; A61K35/17 ; A61P35/00 ; A61K38/20
Abstract:
The present invention provides improved and/or shortened methods for expanding TILs and producing therapeutic populations of TILs, including novel methods for expanding TIL populations in a closed system that lead to improved efficacy, improved phenotype, and increased metabolic health of the TILs in a shorter time period, while allowing for reduced microbial contamination as well as decreased costs. Such TILs find use in therapeutic treatment regimens.
Information query
