Invention Grant
- Patent Title: Osmiumtetroxide-based conversion of RNA and DNA containing thiolated nucleotides
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Application No.: US16533988Application Date: 2019-08-07
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Publication No.: US11254982B2Publication Date: 2022-02-22
- Inventor: Ronald Micura , Alexandra Lusser , Christian Riml , Thomas Amort , Catherina Gasser , Isabel Delazer
- Applicant: UNIVERSITY OF INNSBRUCK , MEDICAL UNIVERSITY OF INNSBRUCK
- Applicant Address: AT Innsbruck; AT Innsbruck
- Assignee: UNIVERSITY OF INNSBRUCK,MEDICAL UNIVERSITY OF INNSBRUCK
- Current Assignee: UNIVERSITY OF INNSBRUCK,MEDICAL UNIVERSITY OF INNSBRUCK
- Current Assignee Address: AT Innsbruck; AT Innsbruck
- Agency: Parker Highlander PLLC
- Main IPC: C12P19/34
- IPC: C12P19/34 ; C12Q1/6869
Abstract:
Provided are compositions and methods for the conversion of thiolated nucleotides, and subsequent detection of the converted nucleotides in RNA or DNA. Also provided herein are compositions and methods for the metabolic labeling of RNA and DNA by incorporation of thiolated nucleotides, and their subsequent conversion and detection.
Public/Granted literature
- US20200048700A1 OSMIUMTETROXIDE-BASED CONVERSION OF RNA AND DNA CONTAINING THIOLATED NUCLEOTIDES Public/Granted day:2020-02-13
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