A system provides for ergonomic handheld integration of multiple user interface devices. The system includes a housing defining an internal compartment and including an upper frame extending over the internal compartment. The upper frame defines a peripheral portion and an intermediate support portion, where the intermediate support portion is at least partially raised above the peripheral portion. A pointing device portion is coupled to the housing, which pointing device portion includes a positional tracking sensor disposed in the internal compartment and at least one control button coupled in depressible manner to the upper frame. A keyboard portion is coupled to the housing, which keyboard portion includes a plurality of keys distributed over at least first and second keyboard sections to collectively define a substantially complete keyboard of predetermined type. The first and second keyboard sections are divided by the intermediate support portion extending therebetween.