There are provided a soundproof structure and an opening structure capable of suppressing degradation of sound absorbing characteristics due to resonance vibration. A micro perforated plate having a plurality of through-holes passing therethrough in the thickness direction and a first frame body, which is disposed in contact with one surface of the micro perforated plate and has a plurality of hole portions, are provided. The opening diameter of the hole portion of the first frame body is larger than the opening diameter of the through-hole of the micro perforated plate. The opening ratio of the hole portion of the first frame body is larger than the opening ratio of the through-hole of the micro perforated plate. The resonance frequency of the micro perforated plate in contact with the first frame body is higher than the audible range.