A surgical system is disclosed including a surgical instrument including a replaceable staple cartridge. The replaceable staple cartridge includes a first RFID tag including a first set of information and a sled including a second RFID tag including a second set of information. A retainer includes a third RFID tag including a third set of information. The first set of information, the second set of information, and the third set of information collectively form a unique combination representative of the replaceable staple cartridge. A remote storage system includes a set of compatible combinations. The controller compares the unique combination to the set of compatible combinations to determine if the replaceable staple cartridge is compatible for use with the surgical instrument. The controller prevents at least one operation of the surgical instrument if the controller determines that said unique combination is not compatible for use with the surgical instrument.