Invention Grant
- Patent Title: Nanosome formulations of aprepitant and methods and applications thereof
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Application No.: US16626408Application Date: 2018-06-26
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Publication No.: US11260028B2Publication Date: 2022-03-01
- Inventor: Sydney Ugwu , Xin He , Zengli Fu , Xin Teng , Ming Ji
- Applicant: ForDoz Pharma Corp.
- Applicant Address: US NJ East Windsor
- Assignee: ForDoz Pharma Corp.
- Current Assignee: ForDoz Pharma Corp.
- Current Assignee Address: US NJ East Windsor
- Agency: Florek & Endres PLLC
- Agent Martin Endres
- International Application: PCT/US2018/039552 WO 20180626
- International Announcement: WO2019/005830 WO 20190103
- Main IPC: A61K9/127
- IPC: A61K9/127 ; A61K9/00 ; A61K31/5377 ; A61K47/10 ; A61K47/14 ; A61K47/22 ; A61K47/24 ; A61K47/26 ; A61K47/28 ; A61K47/36 ; A61K45/06

Abstract:
Disclosed herein are pharmaceutical formulations of aprepitant suitable for parenteral administration including intravenous administration. The pharmaceutical formulations are stable and ready-to-use liposomes for the treatment of emesis and are particularly useful for treatment of chemotherapy or surgery-induced nausea and vomiting. Methods of preparation of the aprepitant formulations are also provided.
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