Invention Grant
![[18F]-labelled lactate derivative as PET radiotracer](/docs/US/2022-03-01/US11260036B2/abs.jpg.600x600.jpg)
- Patent Title: [18F]-labelled lactate derivative as PET radiotracer
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Application No.: US17015431Application Date: 2020-09-09
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Publication No.: US11260036B2Publication Date: 2022-03-01
- Inventor: Pierre Sonveaux , Daniel Labar , Vincent Van Hée , Gwenaël Dehon , Raphaël Frédérick
- Applicant: GRANDIS
- Applicant Address: BE Woluwé-Saint-Lambert
- Assignee: GRANDIS
- Current Assignee: GRANDIS
- Current Assignee Address: BE Woluwé-Saint-Lambert
- Agency: Maier & Maier, PLLC
- Priority: EP16188093 20160909
- Main IPC: A61K31/19
- IPC: A61K31/19 ; A61B6/03 ; A61B6/00 ; C07C59/115 ; C07B59/00
![[18F]-labelled lactate derivative as PET radiotracer](/abs-image/US/2022/03/01/US11260036B2/abs.jpg.150x150.jpg)
Abstract:
A positron emission tomography (PET) radiotracer for imaging lactate uptake, wherein the tracer is [18F]-3-fluoro-2-hydroxypropionic acid, or a pharmaceutical acceptable salt and/or solvate thereof. Also, a process for the radiosynthesis of [18F]-3-fluoro-2-hydroxypropionic acid, or a pharmaceutical acceptable salt and/or solvate thereof. Further, the use of [18F]-3-fluoro-2-hydroxypropionic acid, or a pharmaceutical acceptable salt and/or solvate thereof, for imaging lactate uptake in living cells, especially in humans.
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