![Combination comprising palbociclib and 6-(2,4-dichlorophenyl)-5-[4-[(3S)-1-(3-fluoropropyl)pyrrolidin-3-yl]oxyphenyl]-8,9-dihydro-7H-benzo[7] annulene-2-carboxylic acid and its use for the treatment of cancer](/docs/US/2022-03-01/US11260057B2/abs.jpg.600x600.jpg)
- Patent Title: Combination comprising palbociclib and 6-(2,4-dichlorophenyl)-5-[4-[(3S)-1-(3-fluoropropyl)pyrrolidin-3-yl]oxyphenyl]-8,9-dihydro-7H-benzo[7] annulene-2-carboxylic acid and its use for the treatment of cancer
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Application No.: US16634089Application Date: 2018-07-23
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Publication No.: US11260057B2Publication Date: 2022-03-01
- Inventor: Monsif Bouaboula , Maysoun Shomali , Fangxian Sun
- Applicant: SANOFI
- Applicant Address: FR Paris
- Assignee: SANOFI
- Current Assignee: SANOFI
- Current Assignee Address: FR Paris
- Agency: Hoxie & Associates LLC
- Priority: EP17305998 20170725
- International Application: PCT/EP2018/069901 WO 20180723
- International Announcement: WO2019/020559 WO 20190131
- Main IPC: A61K31/519
- IPC: A61K31/519 ; A61K31/40
![Combination comprising palbociclib and 6-(2,4-dichlorophenyl)-5-[4-[(3S)-1-(3-fluoropropyl)pyrrolidin-3-yl]oxyphenyl]-8,9-dihydro-7H-benzo[7] annulene-2-carboxylic acid and its use for the treatment of cancer](/abs-image/US/2022/03/01/US11260057B2/abs.jpg.150x150.jpg)
Abstract:
Herein are provided a combination of palbociclib and of 6-(2,4-dichlorophenyl)-5-[4-[(3S)-1-(3-fluoropropyl)pyrrolidin-3-yl]oxyphenyl]-8,9-dihydro-7H-benzo[7]annulene-2-carboxylic acid or a pharmaceutically acceptable salt thereof, a pharmaceutical composition containing such a combination, and the therapeutic uses thereof, in particular for the treatment of cancer, including breast cancer.
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