Disclosed are various embodiments for an anti-reflux nasal aspirator that includes a nozzle comprising a nozzle outlet, a bulb configured to provide suction at the nozzle outlet in response to a squeezing force applied to the bulb, an anti-reflux coupler positioned between the bulb and the nozzle through which air passes from the bulb to the nozzle, and a one-way air valve positioned in an aperture located at a base of the bulb. The anti-reflux coupler may include a check valve configured to prevent reflux of debris into the bulb. The check valve may include one of an umbrella valve; a duckbill valve; a slit-cutting valve; and a flapper valve.