A filter cartridge configured to be removably positionable within an inner opening of a housing, wherein the filter cartridge includes a media pack having an inlet end, an outlet end, and an outer surface having an outer peripheral shape, at least one of: (a) a frame member at least partially surrounding the media pack, the frame member including a frame wall having a shape that is different from the outer perimeter shape of the media pack; and (b) a shell at least partially surrounding the media pack, the shell including a shell wall having a shape that is different from the outer perimeter shape of the media pack, and a sealing member extending at least partially around the inlet end of the media pack, wherein the sealing member connects the media pack to at least one of the frame member and the shell.