Invention Grant
- Patent Title: Lateral-flow assay device having flow constrictions
-
Application No.: US16054024Application Date: 2018-08-03
-
Publication No.: US11260390B2Publication Date: 2022-03-01
- Inventor: Zhong Ding , Edward R. Scalice , Daniel P. Salotto
- Applicant: ORTHO-CLINICAL DIAGNOSTICS, INC.
- Applicant Address: US NJ Raritan
- Assignee: ORTHO-CLINICAL DIAGNOSTICS, INC.
- Current Assignee: ORTHO-CLINICAL DIAGNOSTICS, INC.
- Current Assignee Address: US NJ Raritan
- Agency: K&L Gates LLP
- Agent Louis C. Cullman; Brian J. Novak
- Main IPC: G01N33/543
- IPC: G01N33/543 ; B01L3/00

Abstract:
A lateral-flow assay device includes a substrate having a sample addition zone and a wash addition zone downstream thereof along a fluid flow path through which a sample flows. The fluid flow path is configured to receive a wash fluid in the wash addition zone. A hydrophilic surface is arranged in the wash addition zone. Flow constriction(s) are spaced apart from the fluid flow path and arranged to define, with the hydrophilic surface, a reservoir configured to retain the wash fluid by formation of a meniscus between the hydrophilic surface and the flow constriction(s). The fluid flow path draws the wash fluid from the reservoir by capillary pressure. Apparatus for analyzing a fluidic sample and methods of displacing a fluidic sample in a fluid flow path of an assay device are also described.
Public/Granted literature
- US20180345277A1 LATERAL-FLOW ASSAY DEVICE HAVING FLOW CONSTRICTIONS Public/Granted day:2018-12-06
Information query
IPC分类: