A ventilation module for a rail vehicle contains a housing having an air inlet, an air outlet, a dust discharge opening, a first cleaning station in an upper region of the housing, a cyclone separator which has a dust outlet and a cyclone air outlet. A second cleaning stage is disposed in a central region of the housing, which is arranged underneath the first cleaning stage such that air from the cyclone air outlet can reach the second cleaning stage. A dust discharge channel is connected to the dust outlet and is arranged in the central region. A dust discharge fan is set up to extract air and dust from the dust discharge channel and to remove the same through the dust discharge opening. A machine room fan is arranged in a lower region of the housing and is set up to extract air through the second cleaning station.