Invention Grant
- Patent Title: Biaryl derivative as GPR120 agonist
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Application No.: US15539310Application Date: 2015-12-23
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Publication No.: US11261186B2Publication Date: 2022-03-01
- Inventor: Young Kwan Kim , Sang Yun Park , Hyun Woo Joo , Eun Sil Choi , Seung Yup Paek , Seung Wan Kang , Byung Gyu Kim , Chang Seok Lee , Sung Wook Kim , Sang Dae Lee
- Applicant: LG CHEM, LTD.
- Applicant Address: KR Seoul
- Assignee: LG CHEM, LTD.
- Current Assignee: LG CHEM, LTD.
- Current Assignee Address: KR Seoul
- Agency: Rothwell, Figg, Ernst & Manbeck, P.C.
- Priority: KR10-2014-0188399 20141224
- International Application: PCT/KR2015/014178 WO 20151223
- International Announcement: WO2016/105118 WO 20160630
- Main IPC: C07D239/34
- IPC: C07D239/34 ; C07D401/10 ; C07D403/10 ; C07D471/04 ; C07D487/04 ; C07D401/04 ; A61K31/4725 ; C07C59/31 ; C07C229/42 ; C07C229/44 ; C07C317/22 ; C07D207/06 ; C07D209/08 ; C07D211/34 ; C07D213/30 ; C07D213/64 ; C07D213/70 ; C07D231/56 ; C07D235/16 ; C07D241/18 ; C07D261/08 ; C07D277/34 ; C07D307/42 ; C07D307/80 ; C07D311/58 ; C07D317/46 ; C07D317/72 ; C07D333/16 ; C07D401/12 ; C07D401/14 ; C07D405/04 ; C07D405/12 ; C07D405/14 ; C07D407/04 ; C07D409/04 ; C07D409/10 ; C07D409/14 ; C07D413/10 ; C07D413/12 ; C07D417/10
Abstract:
Compounds having the chemical formula 1, a method for producing the compounds of chemical formula 1, a pharmaceutical composition comprising same, and use thereof as a GPR120 agonist for prevention or treatment of inflammation or metabolic diseases such as diabetes, complications from diabetes, obesity, non-alcoholic fatty liver disease, fatty liver disease, and osteoporosis.
Public/Granted literature
- US20170349594A1 BIARYL DERIVATIVE AS GPR120 AGONIST Public/Granted day:2017-12-07
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