Invention Grant
- Patent Title: Alpha-hemolysin variants
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Application No.: US16917435Application Date: 2020-06-30
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Publication No.: US11261488B2Publication Date: 2022-03-01
- Inventor: Timothy Kellogg Craig , Cynthia Ann Cech , Michael Dorwart , Liv Elisabeth Jensen , Marshall Winston Porter , Christos Tzitzilonis , Alexander Hyun-min Yang
- Applicant: Roche Sequencing Solutions, Inc.
- Applicant Address: US CA Pleasanton
- Assignee: Roche Sequencing Solutions, Inc.
- Current Assignee: Roche Sequencing Solutions, Inc.
- Current Assignee Address: US CA Pleasanton
- Agency: FisherBroyles, LLP
- Agent Victoria L. Boyd; Jason M. Pass
- Main IPC: C07K14/31
- IPC: C07K14/31 ; C12Q1/6869
Abstract:
Described herein are engineered alpha-hemolysin subunits having mutated oligomerization domains for assembling into heptameric nanopores in lipid bilayers.
Public/Granted literature
- US20200325534A1 ALPHA-HEMOLYSIN VARIANTS Public/Granted day:2020-10-15
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