Translation lookaside buffer (TLB) invalidation using virtual addresses is provided. A cache is searched for a virtual address matching the input virtual address. Based on a matching virtual address in the cache, the corresponding cache entry is invalidated. The load/store queue is searched for a set and a way corresponding to the set and the way of the invalidated cache entry. Based on an entry in the load/store queue matching the set and the way of the invalidated cache entry, the entry in the load/store queue is marked as pending. Indicating a completion of the TLB invalidate instruction is delayed until all pending entries in the load/store queues are complete.