An audio riser active electrical supervision system includes a high-voltage audio alert system connected to a riser circuit. The high-voltage audio alert system disconnects a high-voltage analog signal from the riser circuit when the audio riser active electrical supervision system operates in a standby mode, and connects the high-voltage analog signal to the riser circuit when the audio riser active electrical supervision system operates in an active alert mode. A plurality of isolator modules operate in a closed state that connects a circuit node to the riser circuit and an open state that disconnects the respective circuit node from the riser circuit. A riser supervision circuit is connected to at least one isolator module to detect a circuit fault on the riser circuit when the audio riser active electrical supervision system operates in the standby mode and the active alert mode.