Treatment of portal hypertension and restoration of liver function using L-ornithine phenylacetate

Invention Grant

US11266620B2 Treatment of portal hypertension and restoration of liver function using L-ornithine phenylacetate 有权

Patent Title: Treatment of portal hypertension and restoration of liver function using L-ornithine phenylacetate
Application No.: US15817847

Application Date: 2017-11-20
Publication No.: US11266620B2

Publication Date: 2022-03-08
Inventor: Rajiv Jalan , Keith Anderson
Applicant: UCL BUSINESS PLC , Ocera Therapeutics, Inc.
Applicant Address: GB London; US CA Redwood City
Assignee: UCL BUSINESS PLC,Ocera Therapeutics, Inc.
Current Assignee: UCL BUSINESS PLC,Ocera Therapeutics, Inc.
Current Assignee Address: GB London; US CA Redwood City
Agency: Knobbe, Martens, Olson & Bear, LLP
Main IPC: A61K31/198
IPC: A61K31/198 ; A61P1/16 ; A61K31/192 ; A61K31/195 ; A61P29/00 ; A61K31/19

Abstract:

Disclosed herein are methods of treating and/or preventing portal hypertension and/or restoring liver function using L-ornithine phenylacetate.

Public/Granted literature

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Espacenet

IPC分类:

A	人类生活必需
A61	医学或兽医学；卫生学
A61K	医用、牙科用或梳妆用的配制品（专门适用于将药品制成特殊的物理或服用形式的装置或方法A61J3/00；空气除臭，消毒或灭菌，或者绷带、敷料、吸收垫或外科用品的化学方面，或材料的使用入A61L；肥皂组合物入C11D）
A61K31/00	含有机有效成分的医药配制品
A61K31/185	.酸；酐、卤化物或其盐类，例如硫酸类、亚氨酸、腙酸或羟肟酸（异羟肟酸入A61K31/16；过酸入A61K31/327）
A61K31/19	..羧酸；例如丙戊酸（水杨酸入A61K31/60）
A61K31/195	...含氨基的
A61K31/197	....有与同一无环碳链相连的氨基和羧基的，例如γ氨基丁酸（GABA）、β丙氨酸、ε氨基己酸、泛酸（肉碱入A61K31/205）
A61K31/198	.....α-氨基酸，例如丙氨酸、乙二胺四乙酸（EDTA）（甜菜碱入A61K31/205；脯氨酸入A61K31/401；色氨酸入A61K31/405；组氨酸入A61K31/4172；未降解为单个氨基酸的肽入A61K38/00）