Invention Grant
- Patent Title: Use of hexokinase 2/mitochondria-detaching compounds for treating hexokinase-2 (HK2)-expressing cancers
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Application No.: US15576825Application Date: 2017-11-07
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Publication No.: US11266639B2Publication Date: 2022-03-08
- Inventor: Vered Behar , Oren Menahem Becker , Hadas Tamar Pahima , Reut Yosef Hamo
- Applicant: Vidac Pharma Ltd.
- Applicant Address: IL Jerusalem
- Assignee: Vidac Pharma Ltd.
- Current Assignee: Vidac Pharma Ltd.
- Current Assignee Address: IL Jerusalem
- Agency: Pearl Cohen Zedek Latzer Baratz LLP
- Agent Mark S. Cohen
- International Application: PCT/IL2017/051214 WO 20171107
- International Announcement: WO2018/083705 WO 20180511
- Main IPC: A61K31/47
- IPC: A61K31/47 ; A61K31/496 ; A61P35/00 ; A61P35/02 ; A61K45/06 ; A61K9/00 ; A61K9/06 ; A61K51/04 ; C12Q1/6886 ; A61K31/506 ; A61K39/395

Abstract:
The present invention provides methods of use of hexokinase 2 (HK2)/mitochondria-detaching compounds, including jasmonate derivatives and piperazine derivatives and pharmaceutical compositions including such compounds for treating, inhibiting, or suppressing a hexokinase-2 (HK2)-expressing cancer.
Public/Granted literature
- US20180303820A1 USE OF HEXOKINASE 2/MITOCHONDRIA-DETACHING COMPOUNDS FOR TREATING HEXOKINASE-2 (HK2)-EXPRESSING CANCERS Public/Granted day:2018-10-25
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