Invention Grant
- Patent Title: Restimulation of cryopreserved tumor infiltrating lymphocytes
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Application No.: US17480941Application Date: 2021-09-21
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Publication No.: US11266694B2Publication Date: 2022-03-08
- Inventor: Ian Frank , Michael T. Lotze
- Applicant: Iovance Biotherapeutics Inc.
- Applicant Address: US CA San Carlos
- Assignee: Iovance Biotherapeutics Inc.
- Current Assignee: Iovance Biotherapeutics Inc.
- Current Assignee Address: US CA San Carlos
- Agency: Morgan, Lewis & Bockius LLP
- Main IPC: C12N5/0783
- IPC: C12N5/0783 ; A01N1/02 ; G01N33/50 ; C12N15/85 ; C07K16/00 ; C07K14/725 ; A61K35/17 ; A61P35/00
Abstract:
The present disclosure provides methods for re-stimulating TIL populations that lead to improved phenotype and increased metabolic health of the TILs and provides methods of assaying for TIL populations to determine suitability for more efficacious infusion after re-stimulation.
Public/Granted literature
- US20220000929A1 RESTIMULATION OF CRYOPRESERVED TUMOR INFILTRATING LYMPHOCYTES Public/Granted day:2022-01-06
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