Invention Grant
- Patent Title: Compositions and methods for treating pathological calcification and ossification
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Application No.: US16813315Application Date: 2020-03-09
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Publication No.: US11266722B2Publication Date: 2022-03-08
- Inventor: Demetrios Braddock , Ronald Albright
- Applicant: YALE UNIVERSITY
- Applicant Address: US CT New Haven
- Assignee: YALE UNIVERSITY
- Current Assignee: YALE UNIVERSITY
- Current Assignee Address: US CT New Haven
- Agency: Saul Ewing Arnstein & Lehr LLP
- Agent Kathryn Doyle; Domingos J. Silva
- Main IPC: C12N9/14
- IPC: C12N9/14 ; A61K38/46 ; C12N9/16
Abstract:
The present invention includes compositions and methods for treating disease and disorders associated with pathological calcification or pathological ossification by modulating the level or activity of NPP1 or a mutant thereof, or a mutant NPP4 modified to exhibit ATP hydrolase activity similar to the hydrolase activity of NPP1.
Public/Granted literature
- US20200237882A1 Compositions and Methods for Treating Pathological Calcification and Ossification Public/Granted day:2020-07-30
Information query
