Invention Grant
- Patent Title: UBE2T peptides and vaccines containing the same
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Application No.: US16120102Application Date: 2018-08-31
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Publication No.: US11266729B2Publication Date: 2022-03-08
- Inventor: Takuya Tsunoda , Ryuji Osawa , Sachiko Yoshimura , Tomohisa Watanabe
- Applicant: OncoTherapy Science, Inc.
- Applicant Address: JP Kanagawa
- Assignee: OncoTherapy Science, Inc.
- Current Assignee: OncoTherapy Science, Inc.
- Current Assignee Address: JP Kanagawa
- Agency: Kilpatrick Townsend & Stockton LLP
- Main IPC: A61K39/00
- IPC: A61K39/00 ; C12N5/0783 ; C12N5/078 ; C07K16/40 ; A61K31/7088 ; C12N9/00 ; G01N33/574

Abstract:
Peptide vaccines against cancer are described herein. In particular, epitope peptides derived from the UBE2T that CTLs are provided. Isolated antigen-presenting cells with CTL inducibility and CTLs that target such peptides, as well as methods for inducing the antigen-presenting cell, or CTL are also provided. The present invention further provides pharmaceutical compositions containing such epitope peptides derived from UBE2T or polynucleotides encoding the polypeptides as active ingredients. Furthermore, the present invention provides methods for the treatment and/or prophylaxis of (i.e., preventing) cancers (tumors), and/or the prevention of a postoperative recurrence thereof, as well as methods for inducing CTLs, methods for inducing anti-tumor immunity, using the epitope peptides derived from UBE2T, polynucleotides encoding the peptides, or antigen-presenting cells presenting the peptides, or the pharmaceutical compositions of the present invention.
Public/Granted literature
- US20180360938A1 UBE2T PEPTIDES AND VACCINES CONTAINING THE SAME Public/Granted day:2018-12-20
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