A robotic palletizer system and method include selectively operating a palletizing robot between at least a pregrouping state, in which the palletizing robot groups to-be-grouped items at a pregrouping station, and a principal grouping state, in which the palletizing robot groups to-be-grouped items at a principal grouping station. The system and method further include selectively operating a load securing machine between a securing state, in which the load securing machine at least partially secures to be grouped items grouped at the principal grouping station, and a non-operational state. The palletizing robot can be operated in the pregrouping state during at least a portion of a time interval during which the load securing machine is operating in the securing state to secure the to-be-grouped items grouped at the principal grouping station.