Invention Grant
- Patent Title: Cyclopropyl ring opening by alpha alkylation of an aldehyde with a polycyclic olefin
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Application No.: US16972081Application Date: 2019-10-14
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Publication No.: US11267776B2Publication Date: 2022-03-08
- Inventor: Julie Quintaine
- Applicant: FIRMENICH SA
- Applicant Address: CH Satigny
- Assignee: FIRMENICH SA
- Current Assignee: FIRMENICH SA
- Current Assignee Address: CH Satigny
- Agency: Armstrong Teasdale LLP
- Priority: EP18200658 20181016
- International Application: PCT/EP2019/077791 WO 20191014
- International Announcement: WO2020/078909 WO 20200423
- Main IPC: C07C45/68
- IPC: C07C45/68 ; C11B9/00 ; C07C47/225

Abstract:
Described herein is a process including alpha alkylation of an aldehyde with a polycyclic olefin followed by a ring opening step in order to provide a compound of formula in a form of any one of its stereoisomers or a mixture thereof and where n represents 1 to 4 and R2 to R5 represent independently of each other, a hydrogen atom or a C1-6 linear alkyl group or a C3-6 branched alkyl group; and R3 and R4 or R5 or, alternatively, R2 and R3 when taken together form a saturated or unsaturated optionally substituted 5 or 6 membered carbocyclic ring.
Public/Granted literature
- US20210230089A1 CYCLOPROPYL RING OPENING BY ALPHA ALKYLATION OF AN ALDEHYDE WITH A POLYCYCLIC OLEFIN Public/Granted day:2021-07-29
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