Invention Grant
- Patent Title: Compound for modulating DDAH and ADMA levels, as well as methods of using thereof to treat disease
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Application No.: US17040832Application Date: 2019-04-30
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Publication No.: US11267780B2Publication Date: 2022-03-08
- Inventor: Jaipal Singh , Kerry Fowler
- Applicant: THE TRUSTEES OF INDIANA UNIVERITY
- Applicant Address: US IN Bloomington
- Assignee: THE TRUSTEES OF INDIANA UNIVERITY
- Current Assignee: THE TRUSTEES OF INDIANA UNIVERITY
- Current Assignee Address: US IN Bloomington
- Agency: Barnes & Thornburg LLP
- International Application: PCT/US2019/030020 WO 20190430
- International Announcement: WO2019/213148 WO 20191107
- Main IPC: C07C65/19
- IPC: C07C65/19 ; C07C65/24 ; C07C65/17 ; C07C233/81 ; C07D257/04 ; C07C317/32 ; C07C211/55 ; C07C323/62 ; C07C215/74 ; C07C65/40 ; C07C49/513 ; C07C63/64 ; C07D209/18 ; C07D263/32 ; C07D213/55 ; C07C65/10 ; C07D295/16 ; C07D277/30 ; C07D333/24 ; C07C233/65
Abstract:
Disclosed are compounds that can modulate DDAH and the amount of asymmetric dimethylarginine (ADMA) in a subject. Also provided are pharmaceutical compositions comprising these compounds, as well as methods of using these compositions to treat and/or prevent diseases associated with elevated or low levels of DDAH and ADMA.
Public/Granted literature
- US20210009498A1 COMPOUND FOR MODULATING DDAH AND ADMA LEVELS, AS WELL AS METHODS OF USING THEREOF TO TREAT DISEASE Public/Granted day:2021-01-14
Information query
