Invention Grant
- Patent Title: Use of small molecule inhibitors to KLF10 for modulation of T regulatory cells and cancer immunotherapy
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Application No.: US15337633Application Date: 2016-10-28
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Publication No.: US11267807B2Publication Date: 2022-03-08
- Inventor: Mark Feinberg , Santosh A. Khedkar
- Applicant: THE BRIGHAM AND WOMEN'S HOSPITAL, INC. , BETH ISRAEL DEACONESS MEDICAL CENTER, INC.
- Applicant Address: US MA Boston; US MA Boston
- Assignee: THE BRIGHAM AND WOMEN'S HOSPITAL, INC.,BETH ISRAEL DEACONESS MEDICAL CENTER, INC.
- Current Assignee: THE BRIGHAM AND WOMEN'S HOSPITAL, INC.,BETH ISRAEL DEACONESS MEDICAL CENTER, INC.
- Current Assignee Address: US MA Boston; US MA Boston
- Agency: Nixon Peabody LLP
- Agent David S. Resnick; Ravinderjit Braich
- Main IPC: C07D409/12
- IPC: C07D409/12 ; C07C49/35 ; C07D207/44 ; C07C39/04 ; C07D311/62 ; C07D239/52 ; C07D239/38 ; C07C233/34 ; C07C251/86 ; C07C49/84 ; C07C39/15 ; C07C205/45 ; C07C217/48
Abstract:
The invention relates to compositions and methods for inhibiting Krüppel-like Factor 10 (KLF10) for modulation of T regulatory cells and cancer immunotherapy.
Public/Granted literature
- US20170121318A1 USE OF SMALL MOLECULE INHIBITORS TO KLF10 FOR MODULATION OF T REGULATORY CELLS AND CANCER IMMUNOTHERAPY Public/Granted day:2017-05-04
Information query
