Invention Grant
- Patent Title: Cell lines for screening odorant and aroma receptors
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Application No.: US15580110Application Date: 2016-06-09
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Publication No.: US11267852B2Publication Date: 2022-03-08
- Inventor: Hyo-Young Jeong , Patrick Pfister , Matthew Rogers
- Applicant: Firmenich SA
- Applicant Address: CH Satigny
- Assignee: Firmenich SA
- Current Assignee: Firmenich SA
- Current Assignee Address: CH Satigny
- Agency: Armstrong Teasdale LLP
- International Application: PCT/US2016/036777 WO 20160609
- International Announcement: WO2016/201153 WO 20161215
- Main IPC: C12N5/00
- IPC: C12N5/00 ; C07K14/47 ; C12N5/10 ; C12N15/85 ; C07K14/705 ; C12N9/22 ; C12N15/11 ; C12N15/86 ; G01N33/50
Abstract:
Provided herein is a cell line with improved odorant receptor function comprising an activated endogenous RTP1 gene, which further expresses an RTP1 protein. Further provided herein is a method for specifically activating an endogenous RTP1 gene in a eukaryotic cell using a CRISPR/Cas9 derived technique. Also provided herein is a method for identifying compounds with desired effects such as perfume or aroma modulators in said cell line.
Public/Granted literature
- US20180298069A1 CELL LINES FOR SCREENING ODORANT AND AROMA RECEPTORS Public/Granted day:2018-10-18
Information query
