- Patent Title: Carbohydrate tethering at cell surfaces to induce immune response
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Application No.: US16775046Application Date: 2020-01-28
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Publication No.: US11267853B2Publication Date: 2022-03-08
- Inventor: Yana K. Reshetnyak , Oleg A. Andreev , Anna Moshnikova , Donald M. Engelman
- Applicant: University of Rhode Island Board of Trustees , Yale University
- Applicant Address: US RI Kingston; US CT New Haven
- Assignee: University of Rhode Island Board of Trustees,Yale University
- Current Assignee: University of Rhode Island Board of Trustees,Yale University
- Current Assignee Address: US RI Kingston; US CT New Haven
- Agency: Mintz Levin Cohn Ferris Glovsky and Popeo, P.C.
- Agent Ingrid A. Beattie
- Main IPC: A61K38/00
- IPC: A61K38/00 ; C07K14/47 ; A61K47/65 ; A61K9/00 ; A61P35/00 ; A61K47/64
Abstract:
The invention features a compositions and methods for inducing an immune response to targeted cells. The compositions induce targeting of a cell by positioning carbohydrate epitopes on the surface of the cell by conjugation of the epitope to a pH-triggered membrane peptide (pHLIP®).
Public/Granted literature
- US20200262881A1 pHLIP-Mediated Carbohydrate Tethering at Cell Surfaces to Induce Immune Response Public/Granted day:2020-08-20
Information query
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