Invention Grant
- Patent Title: Materials and methods for treatment of hemoglobinopathies
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Application No.: US16267702Application Date: 2019-02-05
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Publication No.: US11268077B2Publication Date: 2022-03-08
- Inventor: Tirtha Chakraborty , Bibhu Prasad Mishra
- Applicant: Vertex Pharmaceuticals Incorporated
- Applicant Address: US MA Boston
- Assignee: Vertex Pharmaceuticals Incorporated
- Current Assignee: Vertex Pharmaceuticals Incorporated
- Current Assignee Address: US MA Boston
- Agency: Wolf, Greenfield & Sacks, P.C.
- Main IPC: C12N9/22
- IPC: C12N9/22 ; A61P7/00 ; A61K31/395 ; A61K35/28 ; A61K38/19 ; C12N5/0789 ; C12N5/074 ; C12N15/11 ; C12N15/113
Abstract:
Materials and methods for treating a patient with hemoglobinopathy, both ex vivo and in vivo and materials and methods for deleting at least a portion of a human beta globin locus on chromosome 11 in a human cell by genome editing and thereby increasing the production of fetal hemoglobin (HbF).
Public/Granted literature
- US20190256829A1 MATERIALS AND METHODS FOR TREATMENT OF HEMOGLOBINOPATHIES Public/Granted day:2019-08-22
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