Invention Grant
- Patent Title: CHO integration sites and uses thereof
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Application No.: US17175025Application Date: 2021-02-12
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Publication No.: US11268109B2Publication Date: 2022-03-08
- Inventor: Ying Shen , Darya Burakov , Gang Chen , James P. Fandl
- Applicant: REGENERON PHARMACEUTICALS, INC.
- Applicant Address: US NY Tarrytown
- Assignee: REGENERON PHARMACEUTICALS, INC.
- Current Assignee: REGENERON PHARMACEUTICALS, INC.
- Current Assignee Address: US NY Tarrytown
- Agency: Scully, Scott, Murphy & Presser, P.C.
- Agent Todd R. Samelman
- Main IPC: C12N15/113
- IPC: C12N15/113 ; C12N15/90 ; C12N15/85
Abstract:
Expression-enhancing nucleotide sequences for eukaryotic expressions systems are provided that allow for enhanced and stable expression of recombinant proteins in eukaryotic cells. Genomic integration sites providing enhanced expression and methods of use thereof are provided for expression of a gene of interest in a eukaryotic cell. Chromosomal loci, sequences, and vectors are provided for enhanced and stable expression of genes in eukaryotic cells.
Public/Granted literature
- US20210171984A1 NOVEL CHO INTEGRATION SITES AND USES THEREOF Public/Granted day:2021-06-10
Information query
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