Invention Grant
- Patent Title: Identification of transglutaminase substrates and uses therefor
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Application No.: US15625784Application Date: 2017-06-16
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Publication No.: US11268120B2Publication Date: 2022-03-08
- Inventor: Thomas Albert , Frank Bergmann , Victor Lyamichev , Jigar Patel , Michael Schraeml , Wojtek Steffen
- Applicant: Roche Sequencing Solutions, Inc.
- Applicant Address: US CA Pleasanton
- Assignee: Roche Sequencing Solutions, Inc.
- Current Assignee: Roche Sequencing Solutions, Inc.
- Current Assignee Address: US CA Pleasanton
- Agency: Foley & Lardner LLP
- Agent Joseph P. Meara
- Main IPC: C07K16/28
- IPC: C07K16/28 ; C07K16/30 ; A61K38/08 ; C12P21/02 ; C12N9/10 ; C07K14/47 ; C07K1/107 ; C07K1/13 ; C07K14/00
Abstract:
According to one aspect, the present disclosure provides a method of identifying a substrate of a transglutaminase using a peptide array comprising a plurality of peptides. The method includes the steps of contacting the peptides in the peptide array with the transglutaminase, allowing the transglutaminase to bind to the peptides, and identifying the substrate of the transglutaminase.
Public/Granted literature
- US20170314054A1 IDENTIFICATION OF TRANSGLUTAMINASE SUBSTRATES AND USES THEREFOR Public/Granted day:2017-11-02
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