A homogenization process for coiled tubing is provided. After being preheated in a sectional manner and quenched and tempered, laser-welded low-carbon alloy steel coiled tubing is spray cooled, and then is tempered to obtain homogeneous silvery coiled tubing. Microstructural uniformity of the silvery coiled tubing after the treatment is greatly improved in a welding seam region, a heat sensing region, and a tube wall, situations in which an outer surface of the coiled tubing is burnt and oxidized in the homogenization process are reduced, and a service life of the coiled tubing is prolonged. Moreover, homogeneous coiled tubing with different yield strengths and tensile strengths can be obtained by changing a temperature of the tempering, so that production costs are reduced.