A method and system are provided for operating an automatically guided container transport vehicle that can be automatically guided during forward driving and during rearward driving. The transport vehicle includes a towing vehicle and a trailer with a loading surface for at least one container. The transport vehicle has a vehicle control system for controlling a steering system and a travel drive of the transport vehicle in such a way that the transport vehicle follows a nominal route. The nominal route is automatically pre-defined taking into account a trajectory of the transport vehicle.