The present disclosure relates to systems, methods, and computer readable media for diagnosing and mitigating memory impact events, such as memory leaks, high memory usage, or other memory issues causing a host node from performing as expected on a cloud computing system. The systems described herein involve receiving locally generated memory usage data from a plurality of host nodes. The systems described herein may aggregate the memory usage data and determine a memory impact diagnosis based on a subset of the aggregated memory usage data. The systems described herein may further apply a mitigation model for mitigating the memory impact event. The systems described herein provide an end-to-end solution for diagnosing and mitigating a variety of memory issues using a dynamic and scalable system that reduces a negative impact of memory leaks and other memory issues on a cloud computing system.