An interrupt signal is provided to a first guest operating system. A bus attachment device receives an interrupt signal from a bus connected module with an interrupt target ID identifying a processor assigned for use by the guest operating system as a target processor for handling the interrupt signal. The bus attachment device translates the received interrupt target ID to a logical processor ID of the target processor using an interrupt table entry stored in a memory section assigned to a second guest operating system hosting the first operating system and forwards the interrupt signal to the target processor for handling. The logical processor ID of the target processor is used to address the target processor directly.