Invention Grant
- Patent Title: Nitroxyl donors with improved therapeutic index
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Application No.: US17063372Application Date: 2020-10-05
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Publication No.: US11273143B2Publication Date: 2022-03-15
- Inventor: Vincent Jacob Kalish , Frederick Arthur Brookfield , Stephen Martin Courtney , Lisa Marie Frost , John P. Toscano
- Applicant: Cardioxyl Pharmaceuticals, Inc.
- Applicant Address: US NC Chapel Hill
- Assignee: Cardioxyl Pharmaceuticals, Inc.
- Current Assignee: Cardioxyl Pharmaceuticals, Inc.
- Current Assignee Address: US NC Chapel Hill
- Agency: Byrne Poh LLP
- Agent Nina R. Horan
- Main IPC: A61K31/341
- IPC: A61K31/341 ; A61K31/18 ; A61P9/04 ; C07C317/14 ; C07D307/64 ; A61K31/255 ; A61K31/343 ; A61K31/381 ; A61K31/404 ; A61K31/42 ; A61K31/433 ; A61K31/4436 ; A61K31/5377 ; A61K31/538 ; A61K47/12 ; A61K47/40 ; A61K31/222 ; A61K31/24 ; A61K9/00 ; A61K9/08
Abstract:
The disclosed subject matter provides N-substituted hydroxylamine derivative compounds, pharmaceutical compositions and kits comprising such compounds, and methods of using such compounds or pharmaceutical compositions. In particular, the disclosed subject matter provides methods of using such compounds or pharmaceutical compositions for treating heart failure.
Public/Granted literature
- US20210015784A1 NITROXYL DONORS WITH IMPROVED THERAPEUTIC INDEX Public/Granted day:2021-01-21
Information query
