Invention Grant
- Patent Title: IL-15 and IL-15RAPLHA sushi domain based immunocytokines
-
Application No.: US14910475Application Date: 2014-08-08
-
Publication No.: US11273204B2Publication Date: 2022-03-15
- Inventor: Alain Gey , Eric Tartour , David Bechard
- Applicant: Cytune Pharma , UNIVERSITE PARIS DESCARTES , ASSISTANCE PUBLIQUE-HOPITAUX DE PARIS
- Applicant Address: FR Nantes; FR Paris; FR Paris
- Assignee: Cytune Pharma,UNIVERSITE PARIS DESCARTES,ASSISTANCE PUBLIQUE-HOPITAUX DE PARIS
- Current Assignee: Cytune Pharma,UNIVERSITE PARIS DESCARTES,ASSISTANCE PUBLIQUE-HOPITAUX DE PARIS
- Current Assignee Address: FR Nantes; FR Paris; FR Paris
- Agency: Kagan Binder, PLLC
- Priority: EP13003963 20130808
- International Application: PCT/EP2014/002181 WO 20140808
- International Announcement: WO2015/018528 WO 20150212
- Main IPC: A61K38/20
- IPC: A61K38/20 ; A61K39/395 ; C07K14/54 ; C07K16/28 ; C07K14/715 ; A61K47/68 ; A61K39/00
Abstract:
The present invention relates to an immunocytokine comprising (a) a conjugate, and (b) an immunomodulatory antibody or a fragment thereof directly or indirectly linked by covalence to said conjugate, wherein said conjugate comprises (i) a polypeptide comprising the amino acid sequence of the interleukin 15 or derivatives thereof, and a polypeptide comprising the amino acid sequence of the sushi domain of the IL-15Rα or derivatives thereof; and uses thereof.
Public/Granted literature
- US20160175459A1 IL-15 AND IL-15RAPLHA SUSHI DOMAIN BASED MODULOKINES Public/Granted day:2016-06-23
Information query
IPC分类:
