Invention Grant
- Patent Title: Therapeutic delivery vesicles
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Application No.: US14784015Application Date: 2014-04-10
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Publication No.: US11274139B2Publication Date: 2022-03-15
- Inventor: Samir El Andaloussi , Oscar Wiklander , Joel Nordin , Edvard Smith , Karl-Henrik Grinnemo , Oscar Simonson
- Applicant: Evox Therapeutics Ltd.
- Applicant Address: GB Oxford
- Assignee: Evox Therapeutics Ltd.
- Current Assignee: Evox Therapeutics Ltd.
- Current Assignee Address: GB Oxford
- Agency: Cooley LLP
- Agent Matthew Pavao; Chun L. Yu
- Priority: SE1300271-2 20130412
- International Application: PCT/SE2014/000047 WO 20140410
- International Announcement: WO2014/168548 WO 20141016
- Main IPC: A61K9/00
- IPC: A61K9/00 ; A61K38/00 ; C07K2/00 ; C07K4/00 ; C07K5/00 ; C07K7/00 ; C07K14/00 ; C07K16/00 ; C07K17/00 ; C07K1/00 ; C07K14/705 ; F01C21/10 ; F01C1/344 ; A61K47/69 ; A61K47/62 ; A61K38/17

Abstract:
The present invention pertains to inter alia therapeutic delivery vesicles, for instance exosomes or microvesicles, comprising polypeptide constructs, methods for producing said therapeutic delivery vesicles, pharmaceutical compositions and medical uses thereof. The therapeutic polypeptide constructs comprised in the extracellular delivery vesicles enable sequestering target molecules of interest, to treat e.g. neuro-inflammatory diseases and cancer.
Public/Granted literature
- US20160137716A1 THERAPEUTIC DELIVERY VESICLES Public/Granted day:2016-05-19
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