The present disclosure relates to a guide robot and a method of operating the same. A guide robot according to the present disclosure includes a voice receiving unit to receive a voice, a controller to determine whether the received voice includes a preset wake-up word, and a wireless communication unit to perform communication with an artificial intelligence (AI) server set to be activated by the preset wake-up word. At this time, the control unit transmits the received voice to the artificial intelligence server, receives result information from the artificial intelligence server, and outputs the received result information, when the received voice includes the preset wake-up word. And, the control unit outputs a response voice selected according to a predetermined reference when the received voice does not include the preset wake-up word. The guide robot may be operated by artificial intelligence.