A method and system for remote diagnosis of a cognitive disorder in humans are provided. The system comprises receive, over a network, at least one facial image of a patient; extracting, from the at least one facial image, at least one facial feature indicative of a cognitive decline; classifying the at least one extracted facial feature using a classifier, wherein the classifier maps a plurality of candidate facial features to a score indicating a stage of a cognitive decline; and determining a positive diagnosis of a cognitive decline of the patient, based on the score provided by the classifier in response to the at least one extracted facial feature.