The present application relates to the field of communications, and in particular to a hybrid beam forming architecture-based calibration compensation method and apparatus for improving the accuracy and effectiveness of calibration compensation. The method comprises: a base station determining a preset calibration weight vector matrix W and a preset first calibration signal matrix S, then transmitting N times consecutively calibration signals through analog transmission channels, calculating, according to the calibration weight vector matrix W, the first calibration signal matrix S and a first received data vector matrix YTX, a transmission channel error matrix ETX, and then performing error compensation on the analog transmission channels based on ETX.