A steerable biopsy device comprises an outer sheath comprising a sheath body having a proximal sheath section and a distal sheath section. The outer sheath further comprises a distal sheath tip and a sheath lumen terminating at a distal port in the distal sheath tip. The biopsy device further comprises a biopsy needle integrated with the sheath body. The biopsy needle is slidably disposed in the sheath lumen. The biopsy needle comprises a needle shaft and a distal needle tip configured for being displaced between a stored position within the sheath lumen and a deployed position outside of the distal port of the distal sheath tip. The biopsy device further comprises an articulation control actuator configured for articulating the distal sheath section, and a needle actuator configured for distally advancing the distal needle tip from the stored position to the deployed position.