Invention Grant
- Patent Title: In situ preparation of cyano-bridged metal nanoparticles within a biocompatible reverse micellar system
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Application No.: US15742719Application Date: 2016-07-08
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Publication No.: US11278568B2Publication Date: 2022-03-22
- Inventor: Jean-Claude Maurel , Elsa Compte , Cyril Lavaud , Yannick Guari , Joulia Guari , Jérôme Long
- Applicant: MEDESIS PHARMA , CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE , UNIVERSITE DE MONTPELLIER
- Applicant Address: FR Baillargues; FR Paris; FR Montpellier
- Assignee: MEDESIS PHARMA,CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE,UNIVERSITE DE MONTPELLIER
- Current Assignee: MEDESIS PHARMA,CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE,UNIVERSITE DE MONTPELLIER
- Current Assignee Address: FR Baillargues; FR Paris; FR Montpellier
- Agency: Arent Fox LLP
- Priority: EP15306135 20150709
- International Application: PCT/EP2016/066269 WO 20160708
- International Announcement: WO2017/005899 WO 20170112
- Main IPC: A61K33/32
- IPC: A61K33/32 ; A61K9/107 ; A61K31/28 ; A61K9/51 ; A61K47/28 ; A61K31/26 ; A61K47/10 ; A61K9/00 ; A61K33/26 ; A61K33/30 ; A61K47/24
Abstract:
The present invention relates to a method for in situ preparation of cyano-bridged coordination polymers as metal nanoparticles within a biocompatible reverse micellar system by mixing at least two reverse micellar systems, each one containing at least one metal salt precursor. The invention also relates to the stabilization of theses nanoparticles by using a biocompatible reverse micellar system. This system takes part of the synthesis as a nanoreactor which comprises at least an acylglycerol, a sterol, lecithin, ethanol and water for the preparation of stable cyano-bridged metal nanoparticles without any use of additional stabilizer agent.
Public/Granted literature
- US20180200295A1 IN SITU PREPARATION OF CYANO-BRIDGED METAL NANOPARTICLES WITHIN A BIOCOMPATIBLE REVERSE MICELLAR SYSTEM Public/Granted day:2018-07-19
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