Invention Grant
- Patent Title: Engineered bacteria secreting therapeutic proteins and methods of use thereof
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Application No.: US16328303Application Date: 2017-08-31
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Publication No.: US11278577B2Publication Date: 2022-03-22
- Inventor: Peter Q. Nguyen , Neel Satish Joshi
- Applicant: President and Fellows of Harvard College
- Applicant Address: US MA Cambridge
- Assignee: President and Fellows of Harvard College
- Current Assignee: President and Fellows of Harvard College
- Current Assignee Address: US MA Cambridge
- Agency: Foley Hoag LLP
- International Application: PCT/US2017/049639 WO 20170831
- International Announcement: WO2018/045184 WO 20180308
- Main IPC: C12P21/06
- IPC: C12P21/06 ; A61K35/74 ; C07K14/245 ; C12P21/02 ; A61P1/00 ; A61K9/00 ; A61K9/02 ; A61K9/20 ; A61K9/48 ; C07K19/00

Abstract:
Engineered bacteria that secrete therapeutic polypeptides, pharmaceutical compositions comprising the bacteria, methods for producing recombinant polypeptides, and methods for using the bacteria for diagnostic and therapeutic purposes are provided.
Public/Granted literature
- US20190201457A1 ENGINEERED BACTERIA SECRETING THERAPEUTIC PROTEINS AND METHODS OF USE THEREOF Public/Granted day:2019-07-04
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