Invention Grant
- Patent Title: Polypeptides derived from Enterococcus and their use for vaccination and the generation of therapeutic antibodies
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Application No.: US15122842Application Date: 2015-02-25
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Publication No.: US11278609B2Publication Date: 2022-03-22
- Inventor: Johannes Hübner , Axel Hartke , Luis Felipe Romero Saavedra
- Applicant: ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG , UNIVERSITE DE CAEN BASSE-NORMANDIE
- Applicant Address: DE Freiburg; FR Caen
- Assignee: ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG,UNIVERSITE DE CAEN BASSE-NORMANDIE
- Current Assignee: ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG,UNIVERSITE DE CAEN BASSE-NORMANDIE
- Current Assignee Address: DE Freiburg; FR Caen
- Agency: Saliwanchik, Lloyd & Eisenschenk
- Priority: EP14157628 20140304
- International Application: PCT/EP2015/053948 WO 20150225
- International Announcement: WO2015/132103 WO 20150911
- Main IPC: A61K39/09
- IPC: A61K39/09 ; C07K14/24 ; C07K16/12 ; A61K39/02 ; A61K39/00
Abstract:
Medicament for the treatment or the prevention of a bacterial infection, characterized in that it contains at least one polypeptide selected from the group of SEQ ID NO: 1 to SEQ ID NO: 9, and contiguous fragments thereof, wherein said at least one polypeptide or contiguous fragment thereof induces opsonic antibodies in a patient in need thereof. The polypeptides or the contiguous fragments thereof according to the present invention can be used for the preparation of a vaccine against an infection against Enterococcus.
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