Invention Grant
- Patent Title: Condensed heterocyclic derivates as BCL-2 inhibitors for the treatment of neoplastic diseases
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Application No.: US16795884Application Date: 2020-02-20
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Publication No.: US11279711B2Publication Date: 2022-03-22
- Inventor: Yi Chen , Yan Lou
- Applicant: Newave Pharmaceutical Inc.
- Applicant Address: US CA Pleasanton
- Assignee: Newave Pharmaceutical Inc.
- Current Assignee: Newave Pharmaceutical Inc.
- Current Assignee Address: US CA Pleasanton
- Agency: McCarter & English, LLP
- Agent Yu Lu; Zhongyu “Alex” Wang
- Main IPC: C07D498/14
- IPC: C07D498/14 ; C07D513/14 ; A61P35/00 ; A61P37/00 ; A61P35/02 ; A61P35/04 ; A61K31/5383 ; A61K31/542 ; A61K45/06

Abstract:
The disclosure includes compounds of Formula (A): wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, and R12, j, k, m, n, Y, W, W1, W2, W3, V, L, Z1, Q1, Q2, Q3, and Q4, are defined herein. Also disclosed is a method for treating a neoplastic disease, an autoimmune disease, or a neorodegenerative disease with these compounds.
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