Invention Grant
- Patent Title: Guanine analogs as telomerase substrates and telomere length affectors
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Application No.: US16784825Application Date: 2020-02-07
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Publication No.: US11279720B2Publication Date: 2022-03-22
- Inventor: Sergei M. Gryaznov , Ronald A. Pruzan , Krisztina Pongracz
- Applicant: Geron Corporation
- Applicant Address: US CA Menlo Park
- Assignee: Geron Corporation
- Current Assignee: Geron Corporation
- Current Assignee Address: US CA Menlo Park
- Agency: Bozicevic, Field & Francis LLP
- Agent Rudy J. Ng
- Main IPC: C07F9/6561
- IPC: C07F9/6561 ; C07D473/18
Abstract:
This invention relates to compounds useful for inhibiting telomere elongation. More specifically, the invention provides nucleotide analogs that are incorporated into telomeres by telomerase thereby inhibiting elongation of telomeres. The compounds are use in treating cancer and other cell proliferative diseases.
Public/Granted literature
- US20200283461A1 Guanine Analogs as Telomerase Substrates and Telomere Length Affectors Public/Granted day:2020-09-10
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