Invention Grant
- Patent Title: Enzyme and application thereof
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Application No.: US16090535Application Date: 2017-03-31
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Publication No.: US11279916B2Publication Date: 2022-03-22
- Inventor: Ping Xu , Hongzhi Tang , Kunzhi Zhang , Geng Wu , Fei Tao
- Applicant: SHANGHAI JIAO TONG UNIVERSITY
- Applicant Address: CN Shanghai
- Assignee: SHANGHAI JIAO TONG UNIVERSITY
- Current Assignee: SHANGHAI JIAO TONG UNIVERSITY
- Current Assignee Address: CN Shanghai
- Agency: Fitch, Even, Tabin & Flannery, LLP
- Priority: CN201610205619.5 20160401
- International Application: PCT/CN2017/078912 WO 20170331
- International Announcement: WO2017/167250 WO 20171005
- Main IPC: C12N9/06
- IPC: C12N9/06 ; A61K38/44 ; A61P25/34
Abstract:
Provides an artificial enzyme obtained by improving upon a sequence of a natural nicotine dehydrogenase, wherein the improvement comprises replacing at least one amino acid hindering product release with an amino acid with smaller side chains, thereby improving a catalytic rate.
Public/Granted literature
- US20190153403A1 ENZYME AND APPLICATION THEREOF Public/Granted day:2019-05-23
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