Invention Grant
- Patent Title: Method for identifying compound for inhibiting an activity of a histone lysine demethylase
-
Application No.: US15835420Application Date: 2017-12-07
-
Publication No.: US11279966B2Publication Date: 2022-03-22
- Inventor: Wen-Ching Wang , Hsing-Jien Kung , Chia-Han Chu , Jing-Moon Yang
- Applicant: NATIONAL TSING HUA UNIVERSITY
- Applicant Address: TW Hsinchu
- Assignee: NATIONAL TSING HUA UNIVERSITY
- Current Assignee: NATIONAL TSING HUA UNIVERSITY
- Current Assignee Address: TW Hsinchu
- Agent Hannah Tien
- Main IPC: C12Q1/26
- IPC: C12Q1/26 ; G16B15/20 ; G16C20/64 ; G16B15/30 ; G16B15/00 ; G16B35/00 ; G16C20/60
Abstract:
A method for identifying a compound that inhibits an activity of a histone lysine demethylase, in which the compound interacts with three sites of a pocket of the histone lysine demethylase generated by using a computer program, an alpha-ketoglutarate (AKG), a methylated lysine, and a NIQ.
Public/Granted literature
- US20180087118A1 METHOD FOR IDENTIFYING COMPOUND FOR INHIBITING AN ACTIVITY OF A HISTONE LYSINE DEMETHYLASE Public/Granted day:2018-03-29
Information query
